Efeito da colina protegida no desempenho produtivo e no microbioma ruminal de cordeiros em crescimento.

Autores

DOI:

https://doi.org/10.56926/repia.v5i1.129

Palavras-chave:

Complexo B de bypass, fermentação ruminal, nutracêutico, nutrição de ruminantes

Resumo

A colina é um nutriente essencial para ruminantes, envolvida em funções metabólicas importantes. O objetivo deste estudo foi avaliar o efeito da suplementação com colina protegida no rúmen (CPR) sobre o desempenho produtivo e o microbioma ruminal em cordeiros. Três cordeiros machos (16 ± 0,45 kg de peso vivo) foram distribuídos em um quadrado latino 3 × 3 com duas repetições. Cada período experimental durou 14 dias. Os animais foram alimentados com uma dieta basal formulada para fornecer 1,15 Mcal de NEg/kg de MS e 15% de proteína bruta. Foram avaliados o ganho médio diário (GMD), o consumo de matéria seca (CMS), a conversão alimentar (CA), o pH, o N-NH₃ ruminal e a concentração bacteriana. A suplementação com CPR aumentou o GMD de forma dependente do tratamento e melhorou a CA sem afetar o CMS (p ≤ 0,05). Não foram observadas alterações significativas no pH ou nas populações bacterianas (p > 0,05), e ambos permaneceram dentro das faixas fisiológicas ideais, sugerindo que o CPDR promove o desempenho produtivo sem comprometer a fermentação ruminal.

Downloads

Não há dados estatísticos.

Referências

Arshad, M., Zenobi, G., Staples, C. R., & Santos, J. E. P. (2020). Meta-analysis of the effects of supplemental rumen-protected choline during the transition period on performance and health of parous dairy cows. Journal of Dairy Science, 103(1), 282–300. https://doi.org/10.3168/jds.2019-16842

Arshad, U., & Santos, J. E. P. (2024). Exploring choline’s important roles as a nutrient for transition dairy cows. Journal of Dairy Science, 107(6), 4357–4369. https://doi.org/10.3168/jds.2023-24050

Baumont, R., Cohen-Salmon, D., Prache, S., & Sauvant, D. (2004). A mechanistic model of intake and grazing behaviour in sheep integrating sward architecture and animal. Animal Feed Science and Technology, 112(1–4), 5–28. https://doi.org/10.1016/j.anifeedsci.2003.10.005

Bindel, D. J., Drouillard, J. S., Titgemeyer, E. C., Wessels, R. H., & Löest, C. A. (2000). Effects of ruminally protected choline and dietary fat on performance and blood metabolites of finishing heifers. Journal of Animal Science, 78(10), 2497–2503. https://doi.org/10.2527/2000.78102497x

Broderick, G. A., & Kang, J. H. (1980). Automated simultaneous determination of ammonia and total amino acids in ruminal fluid and in vitro media. Journal of Dairy Science, 63(1), 64–75. https://doi.org/10.3168/jds.S0022-0302(80)82888-8

Bryant, T. C., Rivera, J. D., Galyean, M. L., Duff, G. C., Hallford, D. M., & Montgomery, T. H. (1999). Effects of dietary level of ruminally protected choline on performance and carcass characteristics of finishing beef steers and on growth and serum metabolites in lambs. Journal of Animal Science, 77(11), 2893–2903. https://doi.org/10.2527/1999.77112893x

Cobos, M. A., Ley de Coss, A., Ramírez, N. D., González, S. S., & Ferrera-Cerrato, R. (2011). Pediococcus acidilactici isolated from the rumen of lambs with rumen acidosis, 16S rRNA identification and sensibility to monensin and lasalocid. Research in Veterinary Science, 90(1), 26–30. https://doi.org/10.1016/j.rvsc.2010.05.006

De Veth, M. J., Artegoitia, M. A., Campagna, S. R., Lapierre, H., Harte, F., & Girard, C. L. (2016). Choline absorption and evaluation of bioavailability markers when supplementing choline to lactating dairy cows. Journal of Dairy Science, 99(12), 1–13. https://doi.org/10.3168/jds.2016-11382

Dehority, B. A. (2003). Rumen microbiology: Rumen bacteria – History, methods of in vitro cultivation and discussion of mixed culture fermentation (pp. 157–176). Nottingham University Press.

Holdorf, H. T., Brown, W. E., Combs, G. J., Henisz, S. J., Kendall, S. J., Caputo, M. J., Ruh, K. E., & White, H. M. (2023). Increasing the prepartum dose of rumen-protected choline: Effects of maternal choline supplementation on growth, feed efficiency, and metabolism in Holstein and Holstein×Angus calves. Journal of Dairy Science, 106(9), 6005–6027. https://doi.org/10.3168/jds.2022-23068

Hou, Q., Sun, X., Wu, T., Li, Z., Jonker, A., You, P., Li, R., Li, J., Tian, W., Li, C., Wang, C., He, Y., Rugoho, I., Cheng, L., & You, M. (2022). Supplementation of graded levels of rumen-protected choline to a pelleted total mixed ration did not improve the growth and slaughter performance of fattening lambs. Frontiers in Veterinary Science, 9, 1034895. https://doi.org/10.3389/fvets.2022.1034895

Huang, B., Khan, M. Z., Kou, X., Chen, Y., Liang, H., Ullah, Q., Khan, N., Khan, A., Chai, W., & Wang, C. (2023). Enhancing metabolism and milk production performance in periparturient dairy cattle through rumen-protected methionine and choline supplementation. Metabolites, 13(10), 1080. https://doi.org/10.3390/metabo13101080

Jin, Y., Li, H., & Wang, H. (2023). Dietary rumen-protected choline supplementation regulates blood biochemical profiles and urinary metabolome and improves growth performance of growing lambs. Animal Biotechnology, 34(3), 563–573. https://doi.org/10.1080/10495398.2021.1984247

Kaler, J., Wassink, G. J., & Green, L. E. (2009). The inter- and intra-observer reliability of a locomotion scoring scale for sheep. Veterinary Journal, 180(2), 189–194. https://doi.org/10.1016/j.tvjl.2007.12.028

Kawas, J. R., García-Mazcorro, J. F., Fimbres-Durazo, H., & Ortega-Cerrilla, M. E. (2020). Effects of rumen-protected choline on growth performance, carcass characteristics and blood lipid metabolites of feedlot lambs. Animals, 10(9), 1580. https://doi.org/10.3390/ani10091580

Kenny, T. C., Scharenberg, S., Abu-Remaileh, M., & Birsoy, K. (2025). Cellular and organismal function of choline metabolism. Nature Metabolism, 7(1), 35–52. https://doi.org/10.1038/s42255-024-01203-8

Lee, C., Hristov, A. N., Cassidy, T. W., Herley, K. S., Lapierre, H., Vargas, G. A., de Veth, M. J., Patton, R. A., & Parys, C. (2012). Rumen-protected lysine, methionine, and histidine increase milk protein yield in dairy cows fed a metabolizable protein deficient diet. Journal of Dairy Science, 95(10), 6042–6056. https://doi.org/10.3168/jds.2012-5581

Ley-de Coss, A. C., Guerra-Medina, E., Chávez-Espinoza, M., Meraz-Romero, E., & Montañez-Valdéz, O. D. (2024). Evaluation of herbal choline and chelated minerals on growth and ruminal bacteria in Katahdin rams. Chilean Journal of Agricultural & Animal Sciences, 40(2), 353–361. https://doi.org/10.4067/S0719-38902024000200353

Li, H., Wang, H., Yu, L., Wang, M., Liu, S., Sun, L., & Chen, Q. (2015). Effects of supplementation of rumen-protected choline on growth performance, meat quality and gene expression in longissimus dorsi muscle of lambs. Archives of Animal Nutrition, 69(5), 340–350. https://doi.org/10.1080/1745039X.2015.1073001

Mendoza, G. D., Oviedo, M. F., Pinos, J. M., Lee, H. A., Vázquez, A., Flores, R., Pérez, F., Roque, A., & Cifuentes, O. (2019). Milk production in dairy cows supplemented with herbal choline and methionine. Revista de la Facultad de Ciencias Agrarias UNCuyo, 52(1), 332–343. https://revistas.uncu.edu.ar/ojs/index.php/RFCA/article/view/3076

Mendoza-Martínez, G. D., Orzuna-Orzuna, J. F., Roque-Jiménez, J. A., Gloria-Trujillo, A., Martínez-Garcia, J. A., Sánchez-López, N., Hernandez-García, P. A., & Lee-Rangel, H. A. (2024). A polyherbal mixture with nutraceutical properties for ruminants: A meta-analysis and review of BioCholine powder. Animals, 14(5), 667. https://doi.org/10.3390/ani14050667

NOM-062-ZOO. (1999). Norma Oficial Mexicana NOM-062-ZOO-1999: Especificaciones técnicas para la producción, cuidado y uso de los animales de laboratorio. Diario Oficial de la Federación. http://www.gob.mx/senasica/documentos

NRC. (2007). Nutrient requirements of small ruminants: Sheep, goats, cervids, and New World camelids. The National Academies Press.

Pinotti, L., Campagnoli, A., Sangalli, L., Rebucci, R., Dell’Orto, V., & Baldi, A. (2004). Metabolism in periparturient dairy cows fed rumen-protected choline. Journal of Animal and Feed Sciences, 13(Suppl. 1), 551–554.

Roque-Jimenez, J. A., Mendoza-Martínez, G. D., Vázquez-Valladolid, A., Guerrero-Gonzalez, M. L., Flores-Ramírez, R., Pinos-Rodríguez, J. M., Loor, J. J., Relling, A. E., & Lee-Rangel, H. A. (2020). Supplemental herbal choline increases 5-hmC DNA on whole blood from pregnant ewes and offspring. Animals, 10(8), 1277. https://doi.org/10.3390/ani10081277

Russell, J. B., & Wilson, D. B. (1996). Why are ruminal cellulolytic bacteria unable to digest cellulose at low pH? Journal of Dairy Science, 79(8), 1503–1509. https://doi.org/10.3168/jds.S0022-0302(96)76510-4

SAS Institute. (2011). SAS® user’s guide: Statistics (Release 9.3). SAS Institute Inc.

Shahsavari, A., D’Occhio, M. J., & Al Jassim, R. (2016). The role of rumen-protected choline in hepatic function and performance of transition dairy cows. British Journal of Nutrition, 116(1), 35–44. https://doi.org/10.1017/S0007114516001641

Suárez-Suárez, N. E., Lee-Rangel, H. A., Lizarazo-Chaparro, A. C., Mendoza-Martínez, G. D., Espinosa-Reyes, G., Hernández-García, P. A., García-López, J. C., Martínez-García, J. A., Álvarez-Fuentes, G., & Roque-Jiménez, J. A. (2023). Effect of the supplementation using an herbal mixture as a choline source during early gestation in Rambouillet ewes. Animals, 13(4), 645. https://doi.org/10.3390/ani13040645

Supriyati, K., Budiarsana, I. G., Praharani, L., Krisnan, R., & Sutama, I. K. (2016). Effect of choline chloride supplementation on milk production and milk composition of Etawah grade goats. Journal of Animal Science and Technology, 58, 30. https://doi.org/10.1186/s40781-016-0113-5

Yadav, S. (2024). Climatic classification of Köppen & Thornthwaite. Geographic Book, Quantum Minds Infotech Pvt. Ltd. https://geographicbook.com/climatic-classification-of-koppen-thornthwaite/

Publicado

2026-04-20

Como Citar

Ley de Coss, A., A. Bran, R. A., Montañez Valdez, O. D., Zambrano Castillo, B., Guerra Medina, C. E., Velasco Fernández, F. de C., & Gamboa López, A. K. (2026). Efeito da colina protegida no desempenho produtivo e no microbioma ruminal de cordeiros em crescimento. Revista Peruana De Investigación Agropecuaria, 5(1), e129. https://doi.org/10.56926/repia.v5i1.129